In its mission to advance cell and gene therapies and regenerative medicine research, Gates Institute serves as a networking hub for its membership with events throughout the year to foster collaboration and provides an opportunity to conduct essential aspects of research cost effectively. We provide numerous benefits to support our diverse members as they navigate each stage of the continuum from basic science to patient benefit. Many of our offerings are enumerated below.
Managed in collaboration with CU Innovations, the Gates Grubstake Fund makes awards of up to $350,000 to investigators who are researching and developing regenerative medicine-related technologies including therapeutics, diagnostics, devices, manufacturing, and platforms.
Startup Toolbox is an important part of the bench-to-bedside operating philosophy of Gates Institute and the Anschutz Medical Campus. The program is co-administered with CU Innovations and provides researchers essential services that are not traditionally funded by medically-oriented grants. These commercialization resources include support for financial modeling and business plans, as well as assistance with regulatory strategy and corporate formation. The novel platform also includes legal strategy and guidance, product development, and Small Business Innovation Resources (SBIR) consultants.
Research Core Facilities provide specialized services to the Gates Institute community on a fee-for-service basis. Cores facilitate research by enabling investigators to outsource experiments that require specialized knowledge and technical abilities not found in most laboratories. Because of the nonprofit design of cores, service pricing for Gates Institute members is significantly below that of commercial entities providing similar services.
Gates Institute’s affiliated Gates Biomanufacturing Facility (GBF) is one of six combined cell therapy and protein manufacturing facilities in the United States and the only one of its kind within an 800-mile radius. The GBF, a first-in-human phase 1 Good Manufacturing Practice (GMP) facility, serves some of the nation’s top regenerative medicine researchers at the CU Anschutz Medical Campus.
The Gates Biomanufacturing Facility provides the following services: process development, scale up, manufacturing of both cell therapy- and protein-based products to cGMP standards, and process documentation to academic researchers, clinicians and early stage biotechnology companies. Utilizing its expertise in quality assurance and control and process development and manufacturing, facility staff help translate bench scale processes to optimized clinical-ready manufacturing processes and perform product manufacturing for early-phase clinical trials. By leveraging our existing current Good Manufacturing Practice (cGMP) facility, trained personnel, qualified equipment and best practices across each of our support services, investigators can significantly accelerate their timeline while minimizing their overall investment.
A key part of Gates Institute's mission is to serve as a focal point for recruitment and retention of top research talent for Colorado, tapping into the resources of the Anschutz Medical Campus and our collaborative partners. Pillars of Gates Institute, including the Gates Biomanufacturing Facility and the Grubstake Fund, have proven attractive to top national researchers and highly-regarded Anschutz researchers as they seek to move their discoveries toward treatments in human patients.
Gates Institute works closely with partners to identify and reach out to top researchers. Our partners include CU Boulder, Anschutz Medical Campus, the University of Colorado School of Medicine, UCHealth, Children’s Hospital Colorado, Colorado State University, Colorado School of Mines, and private industry.
The Gates Summer Internship Program (GSIP) encourages outstanding undergraduates to consider careers in biomedical research in an academic or industry setting by providing 11-week full-time training opportunities at Gates Institute. A committee of Gates Institute faculty selects highly qualified undergraduates to work full-time in Gates Institute members' laboratories at the University of Colorado Anschutz Medical Campus. Mentors are critical to our interns' experiences and crucial to the success of the program.
Gates Institute also supports the Graduate Program in Cell Biology, Stem Cells and Development (CSD) directed by Jeff Moore, PhD, Gates Institute member and Diane G. Wallach Chair in Pediatric Stem Cell Biology. The CSD program is advancing the use of stem cells in the clinic by pursuing fundamental discoveries into how cells function and how cells in embryos form the different tissues of the body. Understanding the molecular and cellular mechanisms that underlie development, disease, stem cell biology and regeneration promotes extensive interaction among labs and fosters a robust intellectual environment.
On the fourth Tuesday of the month, January through October, we offer hourlong presentations spanning a wide range of cell and gene therapy and regenerative medicine topics. These presentations bring together a community of researchers with common interests to collaborate, learn, and advance science.
Gates Institute collaborates closely with CU Innovations to move regenerative medicine technologies from the laboratory into the clinic and commercialization. CU Innovations brings together industry partners, entrepreneurs, and investors to help CU Researchers create biomedical technology that improves quality of life. With expertise in patents, copyrights, and licensing, CU Innovations translates discovery into impact through transparent, flexible, best practice intellectual property management services.